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1

Mammalian single-strand break repair: Mechanisms and links with chromatin

Keith W. Caldecott

Journal:

Year:

2007

Language:

english

File:

PDF, 458 KB

english, 2007

2

DNA Strand Break Repair and Human Genetic Disease

McKinnon, Peter J., Caldecott, Keith W.

Journal:

Annual Review of Genomics and Human Genetics

Year:

2007

Language:

english

File:

PDF, 183 KB

english, 2007

3

Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ

Kalasova, Ilona, Hanzlikova, Hana, Gupta, Neerja, Li, Yun, Altmüller, Janine, Reynolds, John J., Stewart, Grant S., Wollnik, Bernd, Yigit, Gökhan, Caldecott, Keith W.

Journal:

Neurology: Genetics

Year:

2019

Language:

english

File:

PDF, 633 KB

english, 2019

4

Mammalian DNA single-strand break repair: an X-ra(y)ted affair

Keith W. Caldecott

Journal:

Year:

2001

Language:

english

File:

PDF, 267 KB

english, 2001

5

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

El-Khamisy, Sherif F., Saifi, Gulam M., Weinfeld, Michael, Johansson, Fredrik, Helleday, Thomas, Lupski, James R., Caldecott, Keith W.

Journal:

Year:

2005

Language:

english

File:

PDF, 573 KB

english, 2005

6

The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

Ahel, Ivan, Rass, Ulrich, El-Khamisy, Sherif F., Katyal, Sachin, Clements, Paula M., McKinnon, Peter J., Caldecott, Keith W., West, Stephen C.

Journal:

Year:

2006

Language:

english

File:

PDF, 476 KB

english, 2006

7

A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage

Ledesma, Felipe Cortes, El Khamisy, Sherif F., Zuma, Maria C., Osborn, Kay, Caldecott, Keith W.

Journal:

Year:

2009

Language:

english

File:

PDF, 576 KB

english, 2009

8

The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1

Lee, Youngsoo, Katyal, Sachin, Li, Yang, El-Khamisy, Sherif F, Russell, Helen R, Caldecott, Keith W, McKinnon, Peter J

Journal:

Nature Neuroscience

Year:

2009

Language:

english

File:

PDF, 1.37 MB

english, 2009

9

An Achilles' heel for breast cancer?

Caldecott, Keith W, Chalmers, Anthony

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 210 KB

english, 2005

10

Chk1 regulates the density of active replication origins during the vertebrate S phase

Maya-Mendoza, Apolinar, Petermann, Eva, Gillespie, David A F, Caldecott, Keith W, Jackson, Dean A

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

11

TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo

Katyal, Sachin, El-Khamisy, Sherif F, Russell, Helen R, Li, Yang, Ju, Limei, Caldecott, Keith W, McKinnon, Peter J

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 589 KB

english, 2007

12

Reduced ligation during DNA base excision repair supported by BRCA2 mutant cells

Bogliolo, Massimo, Taylor, Richard M, Caldecott, Keith W, Frosina, Guido

Journal:

Year:

2000

Language:

english

File:

PDF, 243 KB

english, 2000

13

Sealing of Chromosomal DNA Nicks during Nucleotide Excision Repair Requires XRCC1 and DNA Ligase IIIα in a Cell-Cycle-Specific Manner

Jill Moser, Hanneke Kool, Ioannis Giakzidis, Keith Caldecott, Leon H.F. Mullenders, Maria I. Fousteri

Journal:

Year:

2007

Language:

english

File:

PDF, 1.53 MB

english, 2007

14

TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks

Sherif F. El-Khamisy, Edgar Hartsuiker, Keith W. Caldecott

Journal:

Year:

2007

Language:

english

File:

PDF, 857 KB

english, 2007

15

Preface

Keith W. Caldecott

Journal:

Year:

2008

Language:

english

File:

PDF, 92 KB

english, 2008

16

Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin

Sherif F. El-Khamisy, Sachin Katyal, Poorvi Patel, Limei Ju, Peter J. McKinnon, Keith W. Caldecott

Journal:

Year:

2009

Language:

english

File:

PDF, 999 KB

english, 2009

17

3rd International Genome Dynamics in Neuroscience Conference: “DNA repair and neurological disease”

Keith W. Caldecott, Vilhelm A. Bohr, Peter J. McKinnon

Journal:

Mechanisms of Ageing and Development

Year:

2011

Language:

english

File:

PDF, 117 KB

english, 2011

18

P IV.4 - P IV.4 Biochemical characterisation of the XRCC1/DNA ligase III human protein complex

Richard Taylor, Keith Caldecott

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 123 KB

english, 1997

19

P IV.7b - P IV.7b Defective ligation of base excision repair patches in XRCC1 mutant cells

Enrico Cappelli, Richard Taylor, Michela Cevasco, Angelo Abbondandolo, Keith Caldecott, Guido Frosina

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1997

Language:

english

File:

PDF, 126 KB

english, 1997

20

Role of a BRCT domain in the interaction of DNA ligase III-α with the DNA repair protein XRCC1

Richard M. Taylor, Bill Wickstead, Sam Cronin, Keith W. Caldecott

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 271 KB

english, 1998

21

Polynucleotide Kinase: A Versatile Molecule Makes a Clean Break

Keith W Caldecott

Journal:

Year:

2002

Language:

english

File:

PDF, 70 KB

english, 2002

22

DNA single-strand breaks and neurodegeneration

Keith W. Caldecott

Journal:

Year:

2004

Language:

english

File:

PDF, 185 KB

english, 2004

23

The ataxia–oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4

Paula M. Clements, Claire Breslin, Emma D. Deeks, Philip J. Byrd, Limei Ju, Pawel Bieganowski, Charles Brenner, Maria-Céu Moreira, A. Malcolm R. Taylor, Keith W. Caldecott

Journal:

Year:

2004

Language:

english

File:

PDF, 445 KB

english, 2004

24

XRCC1 Stimulates Human Polynucleotide Kinase Activity at Damaged DNA Termini and Accelerates DNA Single-Strand Break Repair

Claire J Whitehouse, Richard M Taylor, Angela Thistlethwaite, Hong Zhang, Feridoun Karimi-Busheri, Dana D Lasko, Michael Weinfeld, Keith W Caldecott

Journal:

Year:

2001

Language:

english

File:

PDF, 771 KB

english, 2001

25

DNA Single-Strand Break Repair and Spinocerebellar Ataxia

Keith W. Caldecott

Journal:

Year:

2003

Language:

english

File:

PDF, 172 KB

english, 2003

26

The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks

Joanna I. Loizou, Sherif F. El-Khamisy, Anastasia Zlatanou, David J. Moore, Douglas W. Chan, Jun Qin, Stefania Sarno, Flavio Meggio, Lorenzo A. Pinna, Keith W. Caldecott

Journal:

Year:

2004

Language:

english

File:

PDF, 569 KB

english, 2004

27

XRCC3 and Rad51 Modulate Replication Fork Progression on Damaged Vertebrate Chromosomes

Judith Henry-Mowatt, Dean Jackson, Jean-Yves Masson, Penny A Johnson, Paula M Clements, Fiona E Benson, Larry H Thompson, Shunichi Takeda, Stephen C West, Keith W Caldecott

Journal:

Year:

2003

Language:

english

File:

PDF, 400 KB

english, 2003

28

Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions

Isabelle Plo, Zhi-Yong Liao, Juana M. Barceló, Glenda Kohlhagen, Keith W. Caldecott, Michael Weinfeld, Yves Pommier

Journal:

Year:

2003

Language:

english

File:

PDF, 359 KB

english, 2003

29

XRCC1 and DNA strand break repair

Keith W. Caldecott

Journal:

Year:

2003

Language:

english

File:

PDF, 330 KB

english, 2003

30

APLF promotes the assembly and activity of non-homologous end joining protein complexes

Grundy, Gabrielle J, Rulten, Stuart L, Zeng, Zhihong, Arribas-Bosacoma, Raquel, Iles, Natasha, Manley, Katie, Oliver, Antony, Caldecott, Keith W

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 3.70 MB

english, 2012

31

PARP-3 and APLF Function Together to Accelerate Nonhomologous End-Joining

Stuart L. Rulten, Anna E.O. Fisher, Isabelle Robert, Maria C. Zuma, Michele Rouleau, Limei Ju, Guy Poirier, Bernardo Reina-San-Martin, Keith W. Caldecott

Journal:

Year:

2011

Language:

english

File:

PDF, 1.21 MB

english, 2011

32

The mitotic spindle and DNA damage-induced apoptosis

Penny A Johnson, Paula Clements, Kevin Hudson, Keith W Caldecott

Journal:

Toxicology Letters

Year:

2000

Language:

english

File:

PDF, 304 KB

english, 2000

33

Partial Correction of the Single-Strand Break Repair Defect in the CHO Mutant EM9 by Electroporated Recombinant XRCC1 Protein

KEITH W. CALDECOTT, LAWRENCE H. THOMPSON

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 401 KB

english, 1994

34

Tyrosyl DNA phosphodiesterase 2, an enzyme fit for purpose

Caldecott, Keith W.

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 442 KB

english, 2012

35

DNA strand break repair and neurodegeneration

Rulten, Stuart L., Caldecott, Keith W.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.72 MB

english, 2013

36

One ring to bring them all—The role of Ku in mammalian non-homologous end joining

Grundy, Gabrielle J., Moulding, Hayley A., Caldecott, Keith W., Rulten, Stuart L.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.65 MB

english, 2014

37

Preface

Caldecott, Keith

Journal:

Year:

2014

Language:

english

File:

PDF, 126 KB

english, 2014

38

Cross-sensitivity of γ-ray-sensitive hamster mutants to cross-linking agents

Caldecott, Keith, Jeggo, Penny

Journal:

Mutation Research/DNA Repair

Year:

1991

Language:

english

File:

PDF, 792 KB

english, 1991

39

The induction and reversal of topoisomerase II cleavable complexes formed by nuclear extract from the CHO DNA repair mutant, xrs1

Caldecott, Keith, Banks, Geoffrey, Jeggo, Penny

Journal:

Mutation Research/DNA Repair

Year:

1993

Language:

english

File:

PDF, 1.54 MB

english, 1993

40

Generation of assays and antibodies to facilitate the study of human 5′-tyrosyl DNA phosphodiesterase

Thomson, Graeme, Watson, Amanda, Caldecott, Keith, Denneny, Olive, Depledge, Paul, Hamilton, Nicola, Hopkins, Gemma, Jordan, Allan, Morrow, Christopher, Raoof, Ali, Waddell, Ian, Ogilvie, Donald

Journal:

Analytical Biochemistry

Year:

2013

Language:

english

File:

PDF, 558 KB

english, 2013

41

XRCC1 Protein Interacts with One of Two Distinct Forms of DNA Ligase III

Nash, Rachel A., Caldecott, Keith W., Barnes, Deborah E., Lindahl, Tomas

Journal:

Year:

1997

Language:

english

File:

PDF, 201 KB

english, 1997

42

DNA single-strand break repair

Caldecott, Keith W.

Journal:

Experimental Cell Research

Year:

2014

Language:

english

File:

PDF, 664 KB

english, 2014

43

Biophysical Characterization of Human XRCC1 and Its Binding to Damaged and Undamaged DNA †

Mani, Rajam S., Karimi-Busheri, Feridoun, Fanta, Mesfin, Caldecott, Keith W., Cass, Carol E., Weinfeld, Michael

Journal:

Year:

2004

Language:

english

File:

PDF, 239 KB

english, 2004

44

Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells

Caldecott, Keith W., Tucker, James D., Stanker, Lawrence H., Thompson, Larry H.

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 8.15 MB

english, 1995

45

TDP2–Dependent Non-Homologous End-Joining Protects against Topoisomerase II–Induced DNA Breaks and Genome Instability in Cells and In Vivo

Gómez-Herreros, Fernando, Romero-Granados, Rocío, Zeng, Zhihong, Álvarez-Quilón, Alejandro, Quintero, Cristina, Ju, Limei, Umans, Lieve, Vermeire, Liesbeth, Huylebroeck, Danny, Caldecott, Keith W., Co

Journal:

Year:

2013

Language:

english

File:

PDF, 2.96 MB

english, 2013

46

Construction of human XRCC1 minigenes that fully correct the CHO DNA repair mutant EM9

Caldecott, Keith W., Tucker, James D., Thompson, Larry H.

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 468 KB

english, 1992

47

Identification and Functional Characterizations of N-Terminal α- N -Methylation and Phosphorylation of Serine 461 in Human Poly(ADP-ribose) Polymerase 3

Dai, Xiaoxia, Rulten, Stuart L., You, Changjun, Caldecott, Keith W., Wang, Yinsheng

Journal:

Journal of Proteome Research

Year:

2015

Language:

english

File:

PDF, 3.78 MB

english, 2015

48

The Yin and Yang of DAXX regulation

Caldecott, Keith W

Journal:

Year:

2015

Language:

english

File:

PDF, 440 KB

english, 2015

49

The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function

Breslin, Claire, Hornyak, Peter, Ridley, Andrew, Rulten, Stuart L., Hanzlikova, Hana, Oliver, Antony W., Caldecott, Keith W.

Journal:

Nucleic Acids Research

Year:

2015

Language:

english

File:

PDF, 5.35 MB

english, 2015

50

Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections

Maciejewski, Sonia, Nguyen, Joseph H. C., Gómez-Herreros, Fernando, Cortés-Ledesma, Felipe, Caldecott, Keith W., Semler, Bert L.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.22 MB

english, 2016

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